HLA in Gastrointestinal Inflammatory Disorders
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چکیده
منابع مشابه
Cigarettes and Gastrointestinal Disorders
Background and Objectives: Smoking is an important risk factor for gastrointestinal disorders such as peptic ulcer, Crohn's disease and various cancers. The present study discusses the most important and known effects of smoking on the gastrointestinal tract. Method and Materials: This review uses the keywords Smoking, Gastrointestinal diseases, Inflammation and Cancer in the English database...
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Background: Inflammatory bowel diseases (IBDs), which include ulcerative colitis (UC) and Crohn’s disease (CD), are inflammatory disorders that affect the gastrointestinal tract. A combination of inflammatory cytokines has an important role in IBD development. Genome-wide association studies have shown that polymorphisms in the interleukin-23R gene (IL-23R) increase susceptibility to IBD....
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Introduction: Celiac disease is an autoimmune disease caused by persistent intolerance to gluten, which is causedin people who are genetically predisposed. The disease presents with atrophy of the small intestinal mucosa and gastrointestinal and extra-gastrointestinal manifestations.Environmental factors like gluten and genetic factors such as HLA and non-HLA genes are involved in causing the d...
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Ulcerative colitis (UC) is a nonspecific acute and chronic inflammatory bowel disease that diffusely involves the colonic mucosa. The etiology of UC has not yet been elucidated fully. However, many studies have found that immunologic disorders may play a role in the pathogenesis of UC. In addition, due to an increased frequency of UC in families, especially an increased monozygotic compared...
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The term “inflammatory” bowel disease” applies to idiopathic, chronic inflammatory bowel disease (IBD): Crohn’s disease and ulcerative colitis. They occur among all age groups but a peak incidence in the second and third decades. Most of IBD occur as ulcerative colitis, but the incidence of Crohn’s disease has risen over the past 20 years. These disorder ar...
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